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Following softwares developed in Human Genome Center are available. HGC
ftp server provides mirrors of some databases.

Original Contents

Databases

JSNP

Japanese SNPs DB by IMS and JST (Prof. Nakamura's group)

>JSNP

DBTSS

Database of human transcriptional start sites and full-length cDNAs (Profs Sugano and Nakai)

>DBTSS

Softwares

Open source clustering software

The open source clustering software contains clustering library that can be used to analyze gene expression data, e.g. microarray data, written with C language. The library consists of hierarchical clustering, k-means, k-medians clustering and 2D self-organizing maps. The software also has wrappers for other languages, e.g. Python and Perl.

>Open source clustering software

BioRuby

BioRuby is a bioinformatics library for the object oriented scripting language Ruby. The library contains useful methods for treating biological databases, sequence analysis softwares and web services to make daily tasks easier and to build automated pipelines of the analysis.

>BioRuby

Cell Illustrator

Cell Illustrator is commercial pathway drawing software that can model and simulate metabolic pathway, gene regulatory network and signal-transduction network for in Silico analyses. The software works under Mac OS X, Windows, Linux and Solaris with Java 5.0 or later environment.

>Cell Illustrator

SiGN-SSM

SiGN-SSM is open source software for estimating dynamic gene networks from short time, replicated, and irregular time interval expression data.It is suitable for analyzing temporal regulatory dependencies between genes. You can download executable binaries for Linux, Mac OS X, and Windows, as well as the source code package that can be compiled for various environments.

>SiGN-SSM

Mirrored Contents

Databases

NCBI

Resources provided at NCBI (National Center for Biotechnology Information) including Genomes, SNP, Taxonomy, GEO etc. in addition to the GenBank, RefSeq, and UniGene databases.

>NCBI

EMBL

Nucleotide sequence database by EMBL/EBI.

>EMBL

UniProt

Integrated peptide sequence database by SIB/EBI.

>UniProt

PDB

3D structure database by wwPDB (RCSB, EBI, PDBj).

>PDB

Ensembl

Eukaryotic genome database by Sanger/EBI.

>Ensembl

Golden Path

Human genome database by UCSC.

>Golden Path

Pfam, Rfam

Pfam : Protein family database by Washington University.
Rfam : RNA family database by Washington University.

>Pfam, Rfam

InterPro

Integrated protein family database by EBI.

>InterPro

PROSITE

Protein motif and profile database by SIB.

>PROSITE

EPD

Eukaryotic promoter database by SIB.

>EPD

Softwares

NCBI

Similarity search program package BLAST and its compiled databases.

>NCBI

FASTA

Similarity search program package FASTA, also including SSEARCH.

>FASTA

ClustalW, ClustalX

ClustalW : Multiple sequence alignment program.
ClustalX : Graphical user interface for the ClustalW.

>ClustalW, ClustalX

PHYLIP

Phylogenetic analysis program package.

>PHYLIP

HMMER, INFERNAL

HMMER : Protein family search program by profile hidden Markov models.
INFERNAL : RNA family search program by covariance models.

>HMMER, INFERNAL

EMBOSS

Integrated program package for sequence analysis.

>EMBOSS

InterProScan

Protein family search program for the InterPro database.

>InterProScan

exonerate, Wise2

exonerate : Generic sequence comparison program including protein to genomic DNA mapping.
Wise2 : Program for comparing a protein sequence to a genomic DNA.

>exonerate, Wise2

MEME

Program for discovering motifs within the sequences.

>MEME

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